Return to Nuke 'Em High: Volume 2 is the continuation of Lloyd Kaufman's inspired two-part indie event film. Lauren and Chrissy, two lesbian lovers, must face and defeat the most corrupt and evil forces ever to descend upon Tromaville... and the world!

Return to the Class of Nuke 'Em High follows a young couple that are up against the school glee club. Unfortunately, the glee club has mutated into a gang called The Cretins. When the other students begin to undergo mutations, our couple must solve the mystery and save Tromaville High School.