An evil alien bong crashes on earth. Its intent: world domination. Our stoner heroes are sent to the alien bong planet and held captive by nude alien beauties. Their only hope to escape and...

Larnell、Luanne带着他们的疯狂搞笑再次回归，由于吸烟引起的怪异副作用，他们前往南美寻求治疗。在深山丛林里，他们遇到了致命的危险……